Name
   - Differentially expressed marker genes in cancer cells

Version
   - 1.0.36

Created on
  - 2020-03-02T14:02:58.674645

Modified on
   - 2020-03-02T14:03:42.556061

Created by
   -  [evanh@gwmail.gwu.edu]

Authors
   - 

Checksum
   - f9520107e604a87645b8c289d720bf05

Usability Domain
   - This table may be used as a list of candidate marker genes in cancer cells. This table features the top ten differentially expressed genes in the cells of a cancer type, determined with a Wilcoxon rank-sum test.

Description Domain
   Keywords
   - marker genes
   - disease
   - cancer
   - differential expression
   - cell types
   - scRNA-seq

   Pipeline Steps
   - Step-1: Results of a Wilcoxon rank-sum test measuring differential gene expression for each cell-type against all other cell-types in the cancer type were aggregated into a single table.

Execution Domain
   Scripts

   Software Prerequisites

I/O Domain
   Output Subdomain
      Name: human_cancer_scRNA_markers.csv
      URI: http://data.oncomx.org/ln2wwwdata/reviewed/human_cancer_scRNA_markers.csv
      Name: human_cancer_scRNA_markers.stat.csv
      URI: http://data.oncomx.org/ln2wwwdata/reviewed/human_cancer_scRNA_markers.stat.csv

Fields
      Name: "control_cell_type"
     Description: "Cell-type being compared against in the differential gene expression analysis of a cell-type"
      Unique Values: "8"
      Name: "auc"
     Description: "Area under the curve determined from differential expression analysis"
      Unique Values: "220"
      Name: "marker_gene"
     Description: "Gene symbol of marker gene from top hits of a Wilcoxon rank-sum test"
      Unique Values: "80"
      Name: "test_cell_type"
     Description: "Cell-type being evaluated for differential gene expression"
      Unique Values: "8"
      Name: "fdr"
     Description: "False discovery rate"
      Unique Values: "37"
      Name: "pvalue"
     Description: "pvalue for statistical significance of the reported observation"
      Unique Values: "62"